Design of a Randomized Controlled Trial of a Diabetes Prevention Intervention for American Indian and Alaska Native Men

American Journal of Men’s Health | July-August 2020

Ka’imi Sinclair, PHD, MPH; Cara Carty, PhD; Kelly Gonzales, PHD, MPH; Cassandra Nikolaus, PhD; Lucas Gillespie, BA; and Dedra Buchwald, MD

Type 2 diabetes is a serious global epidemic that disproportionately affects disadvantaged populations. American Indians and Alaska Natives (AIs/ANs) have the highest rates of diabetes in the nation with a prevalence of 14.7% in 2018, more than twice that of non-Hispanic Whites. AI/AN men have the highest prevalence of diagnosed type 2 diabetes (14.5%) compared to non-Hispanic Black (11.4%), non-Hispanic Asian (10.0%), and non-Hispanic White (8.6%) men. Several landmark clinical trials have shown that lifestyle interventions can effectively prevent or delay the onset of diabetes among those at risk, including in AIs/ANs. Despite positive outcomes for AIs/ANs in these studies, very few were men. Read more.